Missouri Southern State University (Missouri Southern, MSSU, or MoSo) is a public university in Joplin, Missouri. It was established in 1937 as Joplin Junior College. The university enrolled 4,087 students in Fall 2023. At its conception, Joplin Junior College had 114 students and only 9 faculty members. In 1964, residents of Jasper County, Missouri approved a $2.5 million bond issue to begin construction on a new campus, where the university is currently located.